Cannabidiol is also known as CBD and is one of at least 113 active cannabinoids identified in the cannabis or hemp plant. It is a major phytocannabinoid, (phyto meaning plant based) accounting for up to 40% of the cannabis plant’s extract. Many believe there exist up to 200 cannabinoids. These phyto cannabinoids interact with the human body’s own cannabinoids called Endocannabinoids.
Cannabidiol (CBD) is one of the most common non-psychoactive cannabinoids in the cannabis plant, occurring in the largest concentrations after THC and THCa. The reason THC is psychoactive is that it interacts with the CB1 receptor. CBD, on the other hand, has no interaction with the CB1 receptor and instead uses a bunch of other receptor sites. In an interesting reversal of CBD’s ability to calm THC psychoactivity, there is a way to transform CBD into THC. It appears that CBD is like THC in that it will break down into the heavily sedating CBN. Aside from being non-psychoactive, CBD is a powerful treatment for seizures, pain, inflammation, cancer, autoimmune diseases, and numerous other conditions.
While THC is also an analgesic and anti-inflammatory, CBD has been shown to even more potent than THC and pharmaceutical drugs. While THC and CBD both cause the user to feel less pain they use entirely different mechanisms of action. THC helps with pain by helping one forget they are in pain, or by distracting them from your pain. CBD works to reduce the amount of pain felt whenever you are hurt, more similar to traditional opiate painkillers.
CBD Oil is non-psychoactive and has a wide range of medical uses, it is highly recommended for the treatment of children, the elderly, and anyone who wants to remain clear-headed while still getting the medical benefits of cannabis. CBD appears to change how THC affects the body making it less psychoactive yet preserving its therapeutic benefits. The vast medical benefits coupled with the lack of psychoactivity have prompted over a dozen states in the United States to pass CBD-only medical cannabis laws, legalizing a part of the plant while keeping the whole plant illegal. This does a disservice to patients because even patients who need a CBD-rich regimen of medicine often need THC, THCa, or CBG; paediatric epilepsy patients use very high ratios of CBD to THC, in the range of 28:1, yet they still need THC at times and can see benefits from using THCa and CBG. Combining different cannabinoids together has been shown to have a stronger effect than any of those cannabinoids would have had on their own, this effect has been called the Entourage Effect. The chart below indicates how CBD rich extracts help with individual conditions.